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DNA in confined geometries: topology effects

Dietler, G (EPFL, Lausanne, Switzerland)
Thursday 06 September 2012, 13:30-14:10

Seminar Room 1, Newton Institute


DNA can be found in confined geometries in different situations: for examples in viruses, in the chromosome or in artificial structures like in microfluidic devices. It is therefore interesting to study the statistical properties of the DNA depending on its length, concentration and topology. We present here data on circular DNA deposited in 2 dimensions with different concentration up to the overlap concentration c* and study also the effect of the length of the circular DNA. We characterize the statistical properties by determining the end-to-end distance as a function of the contour length, the directional correlation function, the area covered by the plasmids, the shape parameters like the sphericity as a function of the concentration.


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