The INI has a new website!

This is a legacy webpage. Please visit the new site to ensure you are seeing up to date information.

Skip to content



Intracellular signalling in a molecular jungle: insights from bacterial chemotaxis

Bray, D (Cambridge)
Wednesday 21 January 2004, 10:00-11.00

Seminar Room 1, Newton Institute


The set of biochemical reactions by which an E. coli bacterium detects and responds to distant sources of attractant or repellent molecules is probably the simplest and best understood example of a cell signalling pathway. The pathway has been saturated genetically and all of its protein components have been isolated, measured biochemically, and their atomic structures determined. We are using detailed computer simulations, tied to experimental data, to ask how the pathway works as an integrated unit. Increasingly we find that the physical location of molecular components within the molecular jungle of the cell interior is crucial for an understanding of their function.

Related Links


MP3MP3 Real AudioReal Audio

Back to top ∧