The Isaac Newton Institute for Mathematical Sciences was formally established as part of the University of Cambridge in 1992, and since then has been devoted to the Mathematical Sciences in the broad sense. The Institute is located on Cambridge's Centre for Mathematical Sciences site, housing the University of Cambridge's Departments of Applied Mathematics & Theoretical Physics and Pure Mathematics & Mathematical Statistics together with the University's mathematical libraries. This is now one of the world's largest, and most active, mathematical campuses. The Institute building itself was designed in close consultation with research mathematicians and was purpose-built in 1992 for intense interaction between working scientists; its facilities are highly praised by visitors. The building is used exclusively for running visitor research programmes and receives over 1000 scientific visitors per annum. As well as a library and lecture rooms, the Institute has large circulation and discussion areas to facilitate brain-storming and impromptu seminars. Conference visitors interact immediately with each other, with other Newton Institute visitors, and with resident Cambridge and UK colleagues.