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Application of model-based designs in drug development

Leonov, S (GlaxoSmithKline)
Tuesday 16 August 2011, 15:30-16:00

Seminar Room 1, Newton Institute


We discuss the use of optimal model-based designs at different stages of drug development. Special attention is given to adaptive model-based designs in dose finding studies and designs for nonlinear mixed models which arise in population pharmacokinetic/pharmacodynamic studies. Examples of software tools and their application are provided


[pdf ]


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