Restitution curve splitting as a mechanism for the bifurcation to alternans
Seminar Room 1, Newton Institute
AbstractCardiac tissue displays a bifurcation in electrical response at rapid pacing rates. Traditionally, this bifurcation has been explained in terms of the slope of the restitution curve, a function that relates the response duration to the duration of the interval preceding it. However, we have recently observed that this curve is not a single-valued function under a wide range of physiological conditions. We will show examples of this restitution curve splitting and discuss the implications.
If it doesn't, something may have gone wrong with our embedded player.
We'll get it fixed as soon as possible.