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Analysis of whole cancer genomes

Campbell, P (Wellcome Trust Sanger Institute)
Wednesday 14 July 2010, 16:00-16:30

Seminar Room 1, Newton Institute


Massively parallel sequencing technologies have revolutionized the field of cancer genomics. On a single platform, it is now possible to identify all somatically acquired mutations of all classes in a given cancer sample in real time. However, a number of challenges to interpreting the data exist, and necessitate the development of carefully tested bioinformatic algorithms. I will present an overview of our approaches for handling the data, focusing on the practical issues, common artefacts and challenges of current methodologies.


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